anaesthesia, Perioperative medicine & pain management

NIHR Portfolio Studies - Open to recruitment:

PQIP: Perioperative Quality Improvement Programme: Patient Study
Principal Investigator: Prof. Anil Hormis
​Sponsor: University College London
The Perioperative Quality Improvement Programme (PQIP) measures complications, mortality and patient reported outcome from major non-cardiac surgery. The ambition is to deliver real benefits to patients by supporting clinicians in using data to improve patient outcomes across the UK, reducing variation in processes of care and supporting implementation of best practice. 
Open to Associate PI scheme
SAPPHIRE: Safe Antimicrobial ProPhylaxis for surgery
Principal Investigator: Prof. Anil Hormis
​Sponsor: Barts Health NHS Trust
Surgical site infection (SSI) affects 1 in 20 surgical patients and is an important cause of avoidable postoperative morbidity.  In addition, 1 in 7 patients carry a label of antimicrobial allergy. This multi-centre observational cohort studies the use of antimicrobial prophylaxis and allergy labelling for surgical patients.
AKIS Registry Study
Principal Investigator: Prof. Anil Hormis
Sponsor: Drug Safety Research Unit
The aim of this study is to assess the utilisation and safety of an intravenous bolus formulation of Akis®  (diclofenac sodium) for use in the prevention and treatment of post-operative pain in the UK secondary care setting. 
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SINFONIA
Principal Investigator: Prof. Anil Hormis
​Sponsor: Belfast Health and Social Care Trust
This study aims to determine whether sugammadex is superior to neostigmine after elective or emergency abdominal surgery or non-cardiac thoracic surgery.

NIHR Portfolio studies - in follow up:

MOPED
Principal Investigator: Prof. Anil Hormis
Sponsor: European Society of Anaesthesiology and Intensive Care
This study will evaluate how outcomes from surgery are linked with how well controlled a patient's diabetes is before an operation. 
​The POPPY Study
Principal Investigator: Prof. Anil Hormis
​Sponsor: University Hospitals Plymouth NHS Trust
This study measures short and long-term patient reported outcomes in UK day-case surgery patients in relation to recovery, post-surgical pain and opiate use. 
VITAL: Volatile vs Total Intravenous Anaesthesia
Principal Investigator: Prof. Anil Hormis
Associate PI: Dr Jake Warrington
​Sponsor: University of Warwick
The VITAL study tests whether total intravenous anaesthesia (TIVA) is superior to inhalation anaesthesia for patients undergoing major non-cardiac surgery.
​PANDOS
Principal Investigator: Prof. Anil Hormis
​Sponsor: University of Aberdeen
This study aims to improve pain management and perioperative opioid use after surgery.
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