Anaesthesia, Perioperative Medicine & Pain Management

anaesthesia, Perioperative medicine & pain management

NIHR Portfolio Studies - Open to recruitment:

PQIP: Perioperative Quality Improvement Programme: Patient Study
Principal Investigator: Prof. Anil Hormis
Sponsor: University College London
The Perioperative Quality Improvement Programme (PQIP) measures complications, mortality and patient reported outcome from major non-cardiac surgery. The ambition is to deliver real benefits to patients by supporting clinicians in using data to improve patient outcomes across the UK, reducing variation in processes of care and supporting implementation of best practice.
Open to Associate PI scheme

AKIS Registry Study
Principal Investigator: Prof. Anil Hormis
Sponsor: Drug Safety Research Unit
The aim of this study is to assess the utilisation and safety of an intravenous bolus formulation of Akis® (diclofenac sodium) for use in the prevention and treatment of post-operative pain in the UK secondary care setting.

SINFONIA
Principal Investigator: Prof. Anil Hormis
Sponsor: Belfast Health and Social Care Trust
This study aims to determine whether sugammadex is superior to neostigmine after elective or emergency abdominal surgery or non-cardiac thoracic surgery.

NIHR Portfolio studies - in follow up:

The POPPY Study
Principal Investigator: Prof. Anil Hormis
Sponsor: University Hospitals Plymouth NHS Trust
This study measures short and long-term patient reported outcomes in UK day-case surgery patients in relation to recovery, post-surgical pain and opiate use.

VITAL: Volatile vs Total Intravenous Anaesthesia
Principal Investigator: Prof. Anil Hormis
Associate PI: Dr Jake Warrington
Sponsor: University of Warwick
The VITAL study tests whether total intravenous anaesthesia (TIVA) is superior to inhalation anaesthesia for patients undergoing major non-cardiac surgery.

PANDOS
Principal Investigator: Prof. Anil Hormis
Sponsor: University of Aberdeen
This study aims to improve pain management and perioperative opioid use after surgery.

nihr portfolio studies - in set up:

LOLIPOP
Principal Investigator: Prof. Anil Hormis
Sponsor: Monash University, Melbourne, Australia and University Hospital Southampton NHS Foundation Trust, UK
This study will evaluate the effectiveness of lidocaine infusions commenced during surgery and extending up to 24 hours postoperatively, on the incidence of moderate or severe chronic post-surgical pain detected one year following surgery in female patients undergoing elective breast surgery.

OSIRIS
Principal Investigator: Professor Anil Hormis
Sponsor: Queen Mary University of London
This study will evaluate the clinical effectiveness of a decision support intervention in a cluster randomised trial to improve shared decision making for high-risk surgical patients and their doctors.