Anaesthesia, Perioperative Medicine & Pain Management

anaesthesia, Perioperative medicine & pain management

NIHR Portfolio Studies - Open to recruitment

PQUIP: Perioperative Quality Improvement Programme: Patient Study
Principal Investigator: Prof. Anil Hormis
Sponsor: University College London
The Perioperative Quality Improvement Programme (PQIP) measures complications, mortality and patient reported outcome from major non-cardiac surgery. The ambition is to deliver real benefits to patients by supporting clinicians in using data to improve patient outcomes across the UK, reducing variation in processes of care and supporting implementation of best practice.
Open to Associate PI scheme

VITAL: Volatile vs Total Intravenous Anaesthesia
Principal Investigator: Prof. Anil Hormis
Associate PI: Dr Jake Warrington
Sponsor: University of Warwick
The VITAL study tests whether total intravenous anaesthesia (TIVA) is superior to inhalational anaesthesia for patients undergoing major non-cardiac surgery.
Open to Associate PI scheme

Result-Hip
Principal Investigator: Prof. Anil Hormis
Sponsor: University of Edinburgh / NHS Lothian
The RESULT-Hip study investigates whether patients with hip fractures have better clinical outcomes when a more liberal practice is used to treat anaemia.
Open to Associate PI scheme

SAPPHIRE: Safe Antimicrobial ProPhylaxis for surgery
Principal Investigator: Prof. Anil Hormis
Sponsor: Barts Health NHS Trust
Surgical site infection (SSI) affects 1 in 20 surgical patients and is an important cause of avoidable postoperative morbidity. In addition, 1 in 7 patients carry a label of antimicrobial allergy. This multi-centre observational cohort studies the use of antimicrobial prophylaxis and allergy labelling for surgical patients.

AKIS Registry Study
Principal Investigator: Prof. Anil Hormis
Sponsor: Drug Safety Research Unit
The aim of this study is to assess the utilisation and safety of an intravenous bolus formulation of Akis® (diclofenac sodium) for use in the prevention and treatment of post-operative pain in the UK secondary care setting.

The POPPY Study
Principal Investigator: Professor Anil Hormis
Sponsor: University Hospitals Plymouth NHS trust
This study measures short and long-term patient reported outcomes in UK day-case surgery patients in relation to recovery, post-surgical pain and opiate use.

SINFONIA
Principal Investigator: Professor Anil Hormis
Sponsor: Belfast Health and Social Care Trust
This study aims to determine whether sugammadex is superior to neostigmine after elective or emergency major abdominal surgery or non-cardiac thoracic surgery.

PANDOS
Principal Investigator: Professor Anil Hormis
Sponsor: University of Aberdeen
This study aims to improve pain management and perioperative opioid use after surgery.

MOPED
Principal Investigator: Professor Anil Hormis
Sponsor: European Society of Anaesthesiology and Intensive Care
This study will evaluate how outcomes from surgery are linked with how well controlled a patient's diabetes is before an operation.

In Follow up (recruitment ended):

CASAP: Children's Acute Surgical Abdomen Programme
Principal Investigator: Prof. Anil Hormis
Sponsor: University College London
CASAP aims is to characterise the type and quality of care being delivered to children undergoing urgent/emergency abdominal surgery (including appendicectomy)