respiratory medicine

NIHR Portfolio Studies - open to recruitment:

ASPECT
Principal Investigator: Prof. Anil Hormis
Sponsor: North Bristol NHS Trust
This study aims to test whether aspirin reduces the risk of a heart attack or stroke in patients who are admitted to hospital with pneumonia. 

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RECOVERY Trial
​Principal Investigator: Prof. Anil Hormis
Sponsor: University of Oxford
RECOVERY is an international clinical trial identifying treatments that may be beneficial for people hospitalised with pneumonia.
RECOVERY started in the UK in early 2020 as the Randomised Evaluation of COVID-19 Therapy, a clinical trial testing treatments for people admitted to hospital with COVID-19 pneumonia. Since then it has identified four life-saving treatments for COVID-19, and shown that several other commonly used treatments were not effective. RECOVERY is now open at sites across Europe, Asia  and Africa and in 2023 expanded to test treatments of other types of pneumonia including influenza and non-viral community-acquired pneumonia.

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​REMAP-CAP: Randomised, Embedded, Multifactorial, Adaptive Platform trial for Community-Acquired Pneumonia
Principal Investigator: Prof. Anil Hormis
Sponsor: University Medical Centre Utrecht / Intensive Care National Audit & Research Centre (ICNARC)
The broad objective of this REMAP is, over time, to determine and continuously update the optimal set of treatments for community-acquired pneumonia. This study will use a study design known as a REMAP, a Randomised, Embedded, Multifactorial, Adaptive Platform trial.

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